The only other fix that I’ve found that works for this is to start a brand new Windows Store project and then add my code back in a piece at a time (and without changes to the code, it’s worked both times I’ve had to do this). As a side note, this seems to popup when I share my project between my Virtual Machine running Windows 8 and my physical Windows 8 box (one is on a domain, the other is an evaluation version of Windows 8). Sure enough, this fixed the problem and I was able to then recompile and run the app. I had this come up again, and this time I tried deleting the bin directory so that Visual Studio would have to recreate everything and I would be sure there were no hanging settings files.
This is just another thing that doesn’t quiet work right that will hopefully be smoothed over by the first service pack. According to MSDN ( (vs._activation_failure) k(TargetFrameworkMoniker-.NETCore,Version%3Dv4.5)&rd=true), there are “no sure ways to fix these errors”.